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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1016/j.clim.2021.108780
|2 doi
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|a pubmed24n1088.xml
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|a (DE-627)NLM326663053
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|a (NLM)34118400
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|a (PII)S1521-6616(21)00117-0
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Felsenstein, Susanna
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS
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|c 2021
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 16.09.2021
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|a Date Revised 25.09.2021
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|a published: Print-Electronic
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|a ErratumIn: Clin Immunol. 2021 Oct;231:108855. - PMID 34561161
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| 500 |
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|a Citation Status MEDLINE
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| 520 |
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|a Copyright © 2021 Elsevier Inc. All rights reserved.
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|a Overlapping clinical features promoted the discussion of whether Kawasaki disease (KD) and PIMS-TS share pathophysiological features and disease outcomes. Medical records from English patients with KD (2015-02/20, N = 27) and PIMS-TS (02/2020-21, N = 34) were accessed to extract information. Children with PIMS-TS were older and more frequently of minority ethnicity background. They patients more commonly exhibited cytopenias and hyperferritinemia, which associated with diffuse cardiac involvement and functional impairment. In some PIMS-TS cases, cardiac pathology developed late, but outcomes were more favorable. In both, KD and PIMS-TS, baseline coronary diameter was a predictor of outcomes. PIMS-TS treatment more frequently included respiratory and cardiovascular support, and corticosteroids with IVIG. Cardiac involvement in PIMS-TS may be the result of a cytokine storm. Though more severe and diffuse when compared to KD, cardiac involvement of PIMS-TS has a more favorable prognosis, which may, after recovery, mitigate the need for long-term follow up
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| 650 |
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4 |
|a Comparative Study
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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| 650 |
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4 |
|a COVID
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| 650 |
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4 |
|a KD
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| 650 |
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4 |
|a Kawasaki
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| 650 |
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4 |
|a MIS-C
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| 650 |
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4 |
|a Outcome
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| 650 |
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4 |
|a PIMS-TS
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| 650 |
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4 |
|a Pediatric
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| 650 |
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4 |
|a Treatment
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| 650 |
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7 |
|a Adrenal Cortex Hormones
|2 NLM
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| 650 |
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7 |
|a Immunoglobulins, Intravenous
|2 NLM
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| 700 |
1 |
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|a Duong, Phuoc
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lane, Steven
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Jones, Caroline
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Pain, Clare E
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hedrich, Christian M
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 229(2021) vom: 01. Aug., Seite 108780
|w (DE-627)NLM098196855
|x 1521-7035
|7 nnns
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| 773 |
1 |
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|g volume:229
|g year:2021
|g day:01
|g month:08
|g pages:108780
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| 856 |
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|u http://dx.doi.org/10.1016/j.clim.2021.108780
|3 Volltext
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