Infrared-Emitting Multimodal Nanostructures for Controlled In Vivo Magnetic Hyperthermia

Infrared-Emitting Multimodal Nanostructures for Controlled In Vivo Magnetic Hyperthermia

© 2021 The Authors. Advanced Materials published by Wiley-VCH GmbH.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 33(2021), 30 vom: 06. Juli, Seite e2100077
1. Verfasser: Ximendes, Erving (VerfasserIn)
Weitere Verfasser: Marin, Riccardo, Shen, Yingli, Ruiz, Diego, Gómez-Cerezo, Diego, Rodríguez-Sevilla, Paloma, Lifante, Jose, Viveros-Méndez, Perla X, Gámez, Francisco, García-Soriano, David, Salas, Gorka, Zalbidea, Carmen, Espinosa, Ana, Benayas, Antonio, García-Carrillo, Nuria, Cussó, Lorena, Desco, Manuel, Teran, Francisco J, Juárez, Beatriz H, Jaque, Daniel
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article in vivo imaging luminescence thermometry magnetic hyperthermia near-infrared fluorescence silver sulfide nanoparticles Contrast Media Fluorescent Dyes Nanocapsules Silver Compounds mehr... silver sulfide 9ZB10YHC1C
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100 1 |a Ximendes, Erving  |e verfasserin  |4 aut 
245 1 0 |a Infrared-Emitting Multimodal Nanostructures for Controlled In Vivo Magnetic Hyperthermia 
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500 |a Date Revised 13.10.2024 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a © 2021 The Authors. Advanced Materials published by Wiley-VCH GmbH. 
520 |a Deliberate and local increase of the temperature within solid tumors represents an effective therapeutic approach. Thermal therapies embrace this concept leveraging the capability of some species to convert the absorbed energy into heat. To that end, magnetic hyperthermia (MHT) uses magnetic nanoparticles (MNPs) that can effectively dissipate the energy absorbed under alternating magnetic fields. However, MNPs fail to provide real-time thermal feedback with the risk of unwanted overheating and impeding on-the-fly adjustment of the therapeutic parameters. Localization of MNPs within a tissue in an accurate, rapid, and cost-effective way represents another challenge for increasing the efficacy of MHT. In this work, MNPs are combined with state-of-the-art infrared luminescent nanothermometers (LNTh; Ag2 S nanoparticles) in a nanocapsule that simultaneously overcomes these limitations. The novel optomagnetic nanocapsule acts as multimodal contrast agents for different imaging techniques (magnetic resonance, photoacoustic and near-infrared fluorescence imaging, optical and X-ray computed tomography). Most crucially, these nanocapsules provide accurate (0.2 °C resolution) and real-time subcutaneous thermal feedback during in vivo MHT, also enabling the attainment of thermal maps of the area of interest. These findings are a milestone on the road toward controlled magnetothermal therapies with minimal side effects 
650 4 |a Journal Article 
650 4 |a in vivo imaging 
650 4 |a luminescence thermometry 
650 4 |a magnetic hyperthermia 
650 4 |a near-infrared fluorescence 
650 4 |a silver sulfide nanoparticles 
650 7 |a Contrast Media  |2 NLM 
650 7 |a Fluorescent Dyes  |2 NLM 
650 7 |a Nanocapsules  |2 NLM 
650 7 |a Silver Compounds  |2 NLM 
650 7 |a silver sulfide  |2 NLM 
650 7 |a 9ZB10YHC1C  |2 NLM 
700 1 |a Marin, Riccardo  |e verfasserin  |4 aut 
700 1 |a Shen, Yingli  |e verfasserin  |4 aut 
700 1 |a Ruiz, Diego  |e verfasserin  |4 aut 
700 1 |a Gómez-Cerezo, Diego  |e verfasserin  |4 aut 
700 1 |a Rodríguez-Sevilla, Paloma  |e verfasserin  |4 aut 
700 1 |a Lifante, Jose  |e verfasserin  |4 aut 
700 1 |a Viveros-Méndez, Perla X  |e verfasserin  |4 aut 
700 1 |a Gámez, Francisco  |e verfasserin  |4 aut 
700 1 |a García-Soriano, David  |e verfasserin  |4 aut 
700 1 |a Salas, Gorka  |e verfasserin  |4 aut 
700 1 |a Zalbidea, Carmen  |e verfasserin  |4 aut 
700 1 |a Espinosa, Ana  |e verfasserin  |4 aut 
700 1 |a Benayas, Antonio  |e verfasserin  |4 aut 
700 1 |a García-Carrillo, Nuria  |e verfasserin  |4 aut 
700 1 |a Cussó, Lorena  |e verfasserin  |4 aut 
700 1 |a Desco, Manuel  |e verfasserin  |4 aut 
700 1 |a Teran, Francisco J  |e verfasserin  |4 aut 
700 1 |a Juárez, Beatriz H  |e verfasserin  |4 aut 
700 1 |a Jaque, Daniel  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Advanced materials (Deerfield Beach, Fla.)  |d 1998  |g 33(2021), 30 vom: 06. Juli, Seite e2100077  |w (DE-627)NLM098206397  |x 1521-4095  |7 nnns 
773 1 8 |g volume:33  |g year:2021  |g number:30  |g day:06  |g month:07  |g pages:e2100077 
856 4 0 |u http://dx.doi.org/10.1002/adma.202100077  |3 Volltext 
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