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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1109/TUFFC.2020.3011666
|2 doi
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|a pubmed24n1044.xml
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|a (DE-627)NLM313215464
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|a (NLM)32746223
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Dadgar, Maryam Motmaen
|e verfasserin
|4 aut
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|a High-Power Phased-Array Transducer Module for the Construction of a System for the Treatment of Deep Vein Thrombosis
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|c 2020
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 19.07.2021
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|a Date Revised 19.07.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Blood clot can be disintegrated by high-intensity focused ultrasound alone through inertial cavitation. There are limitations in using single-element ultrasound transducers for this purpose such as lack of steerability and control of the focus in terms of shape and location. Phased-array transducers being able to rapidly scan over the clots can alleviate this problem. A full 3-D control of the ultrasound beam can be achieved by 2-D electronically steerable arrays. However, the required high-pressure amplitude has not been possible with such arrays. In this work, a 2-D 64-element fully populated phased-array transducer module was designed and fabricated for the high-pressure amplitude required for deep vein thrombosis (DVT). Lateral coupling was considered for the transducer design to decrease the electrical impedance and eliminate the need for electrical matching circuit. PZT-4 with a thickness of 0.35 mm, an element surface area of [Formula: see text] mm, and a length of 6 mm showed a mean electrical impedance of 60.4 ± 11.5 measured for each transducer element facilitating effective electric power transfer from the driving electronics. No breakdown was observed when the voltage was increased gradually to 180 ± 3 Vpp. Operation at 180 Vpp was found to be safe over 10,000 repetitions without reduction in the power, resulting in the average pressure amplitude of 1.01 ± 0.09 MPa at 2 mm from the element surface. These pressure amplitude values indicate that an array of eight modules (80 [Formula: see text] mm) is required to reach to the pressure amplitude needed for DVT. Such arrays are practical with the current technology
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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1 |
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|a Hynynen, Kullervo
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t IEEE transactions on ultrasonics, ferroelectrics, and frequency control
|d 1986
|g 67(2020), 12 vom: 21. Dez., Seite 2710-2716
|w (DE-627)NLM098181017
|x 1525-8955
|7 nnns
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| 773 |
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|g volume:67
|g year:2020
|g number:12
|g day:21
|g month:12
|g pages:2710-2716
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|u http://dx.doi.org/10.1109/TUFFC.2020.3011666
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