High-Power Phased-Array Transducer Module for the Construction of a System for the Treatment of Deep Vein Thrombosis

Blood clot can be disintegrated by high-intensity focused ultrasound alone through inertial cavitation. There are limitations in using single-element ultrasound transducers for this purpose such as lack of steerability and control of the focus in terms of shape and location. Phased-array transducers...

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Bibliographische Detailangaben
Veröffentlicht in:IEEE transactions on ultrasonics, ferroelectrics, and frequency control. - 1986. - 67(2020), 12 vom: 21. Dez., Seite 2710-2716
1. Verfasser: Dadgar, Maryam Motmaen (VerfasserIn)
Weitere Verfasser: Hynynen, Kullervo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Schlagworte:Journal Article Research Support, Non-U.S. Gov't
Beschreibung
Zusammenfassung:Blood clot can be disintegrated by high-intensity focused ultrasound alone through inertial cavitation. There are limitations in using single-element ultrasound transducers for this purpose such as lack of steerability and control of the focus in terms of shape and location. Phased-array transducers being able to rapidly scan over the clots can alleviate this problem. A full 3-D control of the ultrasound beam can be achieved by 2-D electronically steerable arrays. However, the required high-pressure amplitude has not been possible with such arrays. In this work, a 2-D 64-element fully populated phased-array transducer module was designed and fabricated for the high-pressure amplitude required for deep vein thrombosis (DVT). Lateral coupling was considered for the transducer design to decrease the electrical impedance and eliminate the need for electrical matching circuit. PZT-4 with a thickness of 0.35 mm, an element surface area of [Formula: see text] mm, and a length of 6 mm showed a mean electrical impedance of 60.4 ± 11.5 measured for each transducer element facilitating effective electric power transfer from the driving electronics. No breakdown was observed when the voltage was increased gradually to 180 ± 3 Vpp. Operation at 180 Vpp was found to be safe over 10,000 repetitions without reduction in the power, resulting in the average pressure amplitude of 1.01 ± 0.09 MPa at 2 mm from the element surface. These pressure amplitude values indicate that an array of eight modules (80 [Formula: see text] mm) is required to reach to the pressure amplitude needed for DVT. Such arrays are practical with the current technology
Beschreibung:Date Completed 19.07.2021
Date Revised 19.07.2021
published: Print-Electronic
Citation Status MEDLINE
ISSN:1525-8955
DOI:10.1109/TUFFC.2020.3011666