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231225s2020 xx |||||o 00| ||eng c |
| 024 |
7 |
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|a 10.1002/adma.202000660
|2 doi
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5 |
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|a pubmed24n1032.xml
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|a eng
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| 100 |
1 |
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|a Qiu, Jichuan
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Phase-Change Materials for Controlled Release and Related Applications
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|c 2020
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|a Text
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 03.05.2021
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|a Date Revised 12.11.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Phase-change materials (PCMs) have emerged as a novel class of thermo-responsive materials for controlled release, where the payloads encapsulated in a solid matrix are released only upon melting the PCM to trigger a solid-to-liquid phase transition. Herein, the advances over the past 10 years in utilizing PCMs as a versatile platform for the encapsulation and release of various types of therapeutic agents and biological effectors are highlighted. A brief introduction to PCMs in the context of desired properties for controlled release and related applications is provided. Among the various types of PCMs, a specific focus is placed on fatty acids and fatty alcohols for their natural availability, low toxicity, biodegradability, diversity, high abundance, and low cost. Then, various methods capable of processing PCMs, and their mixtures with payloads, into stable suspensions of colloidal particles, and the different means for triggering the solid-to-liquid phase transition are discussed. Finally, a range of applications enabled by the controlled release system based on PCMs are presented together with some perspectives on future directions
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|a Journal Article
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|a Review
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|a controlled release
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|a fatty acids
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|a phase-change materials
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|a stimuli-responsive drug delivery
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|a Colloids
|2 NLM
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| 650 |
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|a Delayed-Action Preparations
|2 NLM
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| 650 |
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|a Fatty Acids
|2 NLM
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| 650 |
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|a Fatty Alcohols
|2 NLM
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| 650 |
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|a Intercellular Signaling Peptides and Proteins
|2 NLM
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| 650 |
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|a Phospholipids
|2 NLM
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| 700 |
1 |
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|a Huo, Da
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Xia, Younan
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 32(2020), 25 vom: 15. Juni, Seite e2000660
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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|g volume:32
|g year:2020
|g number:25
|g day:15
|g month:06
|g pages:e2000660
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|u http://dx.doi.org/10.1002/adma.202000660
|3 Volltext
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