Phase-Change Materials for Controlled Release and Related Applications
© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
| Veröffentlicht in: | Advanced materials (Deerfield Beach, Fla.). - 1998. - 32(2020), 25 vom: 15. Juni, Seite e2000660 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2020
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| Zugriff auf das übergeordnete Werk: | Advanced materials (Deerfield Beach, Fla.) |
| Schlagworte: | Journal Article Review controlled release fatty acids phase-change materials stimuli-responsive drug delivery Colloids Delayed-Action Preparations Fatty Acids Fatty Alcohols mehr... |
| Zusammenfassung: | © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Phase-change materials (PCMs) have emerged as a novel class of thermo-responsive materials for controlled release, where the payloads encapsulated in a solid matrix are released only upon melting the PCM to trigger a solid-to-liquid phase transition. Herein, the advances over the past 10 years in utilizing PCMs as a versatile platform for the encapsulation and release of various types of therapeutic agents and biological effectors are highlighted. A brief introduction to PCMs in the context of desired properties for controlled release and related applications is provided. Among the various types of PCMs, a specific focus is placed on fatty acids and fatty alcohols for their natural availability, low toxicity, biodegradability, diversity, high abundance, and low cost. Then, various methods capable of processing PCMs, and their mixtures with payloads, into stable suspensions of colloidal particles, and the different means for triggering the solid-to-liquid phase transition are discussed. Finally, a range of applications enabled by the controlled release system based on PCMs are presented together with some perspectives on future directions |
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| Beschreibung: | Date Completed 03.05.2021 Date Revised 12.11.2023 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1521-4095 |
| DOI: | 10.1002/adma.202000660 |