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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1109/TUFFC.2020.2989109
|2 doi
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|a pubmed25n1030.xml
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|a eng
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| 100 |
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|a Zhu, Yang
|e verfasserin
|4 aut
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|a Experimental Validation of Perfusion Imaging With HOSVD Clutter Filters
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|c 2020
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|a Text
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|a Date Completed 22.07.2021
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|a Date Revised 03.09.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Novel pulsed-Doppler methods for perfusion imaging are validated using dialysis cartridges as perfusion phantoms. Techniques that were demonstrated qualitatively at 24 MHz, in vivo, are here examined quantitatively at 5 and 12.5 MHz using phantoms with the blood-mimicking fluid flow within cellulose microfibers. One goal is to explore a variety of flow states to optimize measurement sensitivity and flow accuracy. The results show that 2-3-s echo acquisitions at roughly 10 frames/s yield the highest sensitivity to flows of 1-4 mL/min. A second goal is to examine methods for setting the parameters of higher order singular value decomposition (HOSVD) clutter filters. For stationary or moving clutter, the velocity of the blood-mimicking fluid in the microfibers is consistently estimated within measurement uncertainty (mean coefficient of variation = 0.26). Power Doppler signals were equivalent for stationary and moving clutter after clutter filtering, increasing approximately 3 dB/mL/min of blood-mimicking fluid flow for 0 ≤ q ≤ 4 mL/min. Comparisons between phantom and preclinical images show that peripheral perfusion imaging can be reliably achieved without contrast enhancement
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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1 |
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|a Kim, MinWoo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hoerig, Cameron
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Insana, Michael F
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t IEEE transactions on ultrasonics, ferroelectrics, and frequency control
|d 1986
|g 67(2020), 9 vom: 23. Sept., Seite 1830-1838
|w (DE-627)NLM098181017
|x 1525-8955
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|g volume:67
|g year:2020
|g number:9
|g day:23
|g month:09
|g pages:1830-1838
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|u http://dx.doi.org/10.1109/TUFFC.2020.2989109
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