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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.0c00953
|2 doi
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|a pubmed25n1029.xml
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|a (DE-627)NLM308927745
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|a (NLM)32308005
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Katayama, Risa
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Characterization of the Hydration Process of Phospholipid-Mimetic Polymers Using Air-Injection-Mediated Liquid Exclusion Methods
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|c 2020
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 26.08.2020
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|a Date Revised 26.08.2020
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a 2-Methacryloyloxyethyl phosphorylcholine (MPC) polymers including hydrophobic units such as poly(MPC-co-butyl methacrylate) (PMB) and poly(MPC-co-dodecyl methacrylate) (PMD) are used as coating agents for medical devices because of their antifouling effects. In this study, the whole hydration process of MPC polymer-coated surfaces was investigated using air-injection-mediated liquid exclusion (AILE) methods in which the liquid exclusion diameter during air injection was correlated to the water-repelling property. The prejetted and standard AILE methods showed the initial change from a dry to a wet state and the swelling behaviors of the MPC polymers, respectively. The liquid exclusion diameter of the MPC polymer-coated surfaces increased with an increase in the immersion time in various aqueous solutions such as deionized water, phosphate-buffered saline (PBS), and cell culture media. Moreover, the liquid exclusion diameter of the PMD-coated surface was larger than that of the PMB-coated one. Ellipsometry directly indicated the polymer layers swollen in water. Scanning probe microscopy (SPM) revealed that nanosized protuberances were formed in water, especially at the PMD-coated surface. The different swelling behaviors of these MPC polymer-coated surfaces affected the liquid exclusion diameters. Thus, the AILE methods are a powerful tool to elucidate the hydration process in various liquid media
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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1 |
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|a Tanaka, Nobuyuki
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Takagi, Yusuke
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Shiraishi, Kohei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tanaka, Yo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Matsumoto, Akikazu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kojima, Chie
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 36(2020), 20 vom: 26. Mai, Seite 5626-5632
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnas
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| 773 |
1 |
8 |
|g volume:36
|g year:2020
|g number:20
|g day:26
|g month:05
|g pages:5626-5632
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|u http://dx.doi.org/10.1021/acs.langmuir.0c00953
|3 Volltext
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|a GBV_ILN_721
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|a AR
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|d 36
|j 2020
|e 20
|b 26
|c 05
|h 5626-5632
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