Cautionary note on the use of Caenorhabditis elegans to study muscle phenotypes caused by mutations in the human MYH7 gene

Mutations in the human MYH7 gene, encoding a slow skeletal muscle/β-cardiac myosin heavy chain, cause different types of myopathies. The nematode model Caenorhabditis elegans has frequently been employed to study the molecular and physiological consequences of MYH7 mutations in muscle function by in...

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Publié dans:BioTechniques. - 1993. - 68(2020), 6 vom: 29. Juni, Seite 296-299
Auteur principal: Gil-Gálvez, Alejandro (Auteur)
Autres auteurs: Carbonell-Corvillo, Pilar, Paradas, Carmen, Miranda-Vizuete, Antonio
Format: Article en ligne
Langue:English
Publié: 2020
Accès à la collection:BioTechniques
Sujets:Letter Research Support, Non-U.S. Gov't Caenorhabditis elegans MYH7 UNC-54 mutation myosin overexpression Caenorhabditis elegans Proteins MYH7 protein, human plus... UNC-54 protein, C elegans Green Fluorescent Proteins 147336-22-9 Cardiac Myosins EC 3.6.1.- Myosin Heavy Chains EC 3.6.4.1 Myosins