Cautionary note on the use of Caenorhabditis elegans to study muscle phenotypes caused by mutations in the human MYH7 gene

Mutations in the human MYH7 gene, encoding a slow skeletal muscle/β-cardiac myosin heavy chain, cause different types of myopathies. The nematode model Caenorhabditis elegans has frequently been employed to study the molecular and physiological consequences of MYH7 mutations in muscle function by in...

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Veröffentlicht in:BioTechniques. - 1988. - 68(2020), 6 vom: 14. Juni, Seite 296-299
1. Verfasser: Gil-Gálvez, Alejandro (VerfasserIn)
Weitere Verfasser: Carbonell-Corvillo, Pilar, Paradas, Carmen, Miranda-Vizuete, Antonio
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Letter Research Support, Non-U.S. Gov't Caenorhabditis elegans MYH7 UNC-54 mutation myosin overexpression Caenorhabditis elegans Proteins MYH7 protein, human mehr... UNC-54 protein, C elegans Green Fluorescent Proteins 147336-22-9 Cardiac Myosins EC 3.6.1.- Myosin Heavy Chains EC 3.6.4.1 Myosins