TADBD : a sensitive and fast method for detection of typologically associated domain boundaries

A topologically associated domain (TAD) is a self-interacting genomic block. Detection of TAD boundaries on Hi-C contact matrix is one of the most important issues in the analysis of 3D genome architecture at TAD level. Here, we present TAD boundary detection (TADBD), a sensitive and fast computatio...

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Publié dans:BioTechniques. - 1993. - 69(2020), 1 vom: 01. Juli, Seite 376-383
Auteur principal: Lyu, Hongqiang (Auteur)
Autres auteurs: Li, Lin, Wu, Zhifang, Wang, Tian, Zheng, Jiguang, Wang, Hongda
Format: Article en ligne
Langue:English
Publié: 2020
Accès à la collection:BioTechniques
Sujets:Journal Article Research Support, Non-U.S. Gov't Hi-C haar-based algorithm topologically associated boundary detection Chromatin