pH Responsiveness of Hexosomes and Cubosomes for Combined Delivery of Brucea javanica Oil and Doxorubicin

We report pH-responsive liquid crystalline lipid nanoparticles, which are dual-loaded by Brucea javanica oil (BJO) and doxorubicin hydrochloride (DOX) and display a pH-induced inverted hexagonal (pH = 7.4) to cubic (pH = 6.8) to emulsified microemulsion (pH = 5.3) phase transition with a therapeutic...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 45 vom: 12. Nov., Seite 14532-14542
1. Verfasser: Li, Yawen (VerfasserIn)
Weitere Verfasser: Angelova, Angelina, Hu, Fangzhou, Garamus, Vasil M, Peng, Changjun, Li, Na, Liu, Jianwen, Liu, Dan, Zou, Aihua
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibiotics, Antineoplastic Drug Carriers Lipids Plant Oils Doxorubicin 80168379AG