Structural consequences of transforming growth factor beta-1 activation from near-therapeutic X-ray doses

Dissociation of transforming growth factor beta-1 (TGFβ-1) from the inhibitory protein latency-associated peptide (LAP) can occur from low doses of X-ray irradiation of the LAP-TGFβ-1 complex, resulting in the activation of TGFβ-1, and can have health-related consequences. Using the tools and knowle...

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Veröffentlicht in:	Journal of synchrotron radiation. - 1994. - 26(2019), Pt 4 vom: 01. Juli, Seite 967-979
1. Verfasser:	Stachowski, Timothy (VerfasserIn)
Weitere Verfasser:	Grant, Thomas D, Snell, Edward H
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2019
Zugriff auf das übergeordnete Werk:	Journal of synchrotron radiation
Schlagworte:	Journal Article SAXS latency-associated peptide radiation damage transforming growth factor beta-1 Peptides Protein Precursors TGFB1 protein, human Transforming Growth Factor beta Transforming Growth Factor beta1 latency-associated propeptide, TGF-beta