One-Pot Synthesis of Chicken-Feather-Keratin-Based Prodrug Nanoparticles with High Drug Content for Tumor Intracellular DOX Delivery

pH/reduction dual-triggered chicken-feather-keratin-based prodrug nanoparticles (C-PK/- SS-Hy-D NPs) were designed via a facile one-pot oxidation coupling reaction between the thiol-functional acid-labile prodrug M-Hy-D and the PEGylated keratin (PK) graft copolymer, for tumor intracellular doxorubi...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 35(2019), 24 vom: 18. Juni, Seite 8007-8014
Auteur principal: Zhang, Huifang (Auteur)
Autres auteurs: Liu, Peng
Format: Article en ligne
Langue:English
Publié: 2019
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Prodrugs Keratins 68238-35-7 Doxorubicin 80168379AG