One-Pot Synthesis of Chicken-Feather-Keratin-Based Prodrug Nanoparticles with High Drug Content for Tumor Intracellular DOX Delivery

pH/reduction dual-triggered chicken-feather-keratin-based prodrug nanoparticles (C-PK/- SS-Hy-D NPs) were designed via a facile one-pot oxidation coupling reaction between the thiol-functional acid-labile prodrug M-Hy-D and the PEGylated keratin (PK) graft copolymer, for tumor intracellular doxorubi...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 24 vom: 18. Juni, Seite 8007-8014
1. Verfasser: Zhang, Huifang (VerfasserIn)
Weitere Verfasser: Liu, Peng
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Prodrugs Keratins 68238-35-7 Doxorubicin 80168379AG