|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM297027352 |
| 003 |
DE-627 |
| 005 |
20250225075818.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2019 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1021/acs.langmuir.9b00701
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0989.xml
|
| 035 |
|
|
|a (DE-627)NLM297027352
|
| 035 |
|
|
|a (NLM)31083892
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Lv, Shanshan
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Engineering Protein-Clay Nanosheets Composite Hydrogels with Designed Arginine-Rich Proteins
|
| 264 |
|
1 |
|c 2019
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 17.08.2020
|
| 500 |
|
|
|a Date Revised 17.08.2020
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Clay nanosheets (CNSs) have been widely used in the design of nanocomposite biomaterials. CNSs display a disk-like morphology with strong negatively charged surfaces. It has been shown that guanidinium-containing molecules can bind CNSs through noncovalent salt-bridge interactions and thus serve as "molecular glues" for CNSs. Making use of the guanidinium side chain in arginine, here, we designed novel arginine-rich elastomeric proteins to engineer protein-CNS nanocomposite hydrogels. Our results showed that these arginine-rich proteins can interact with CNSs effectively and can cross-link CNSs into hydrogels. Rheological measurements showed that mechanical properties of the resultant hydrogels depended on the arginine content in the arginine-rich proteins as well as CNS/protein concentration. Compared with hydrogels constructed from CNSs or proteins alone, the novel protein-CNS nanocomposite hydrogels show much improved mechanical properties. Our work opens up a new avenue to engineer functional protein hydrogels for various applications
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
7 |
|a Biocompatible Materials
|2 NLM
|
| 650 |
|
7 |
|a Hydrogels
|2 NLM
|
| 650 |
|
7 |
|a Polymers
|2 NLM
|
| 650 |
|
7 |
|a Proteins
|2 NLM
|
| 650 |
|
7 |
|a Arginine
|2 NLM
|
| 650 |
|
7 |
|a 94ZLA3W45F
|2 NLM
|
| 650 |
|
7 |
|a Clay
|2 NLM
|
| 650 |
|
7 |
|a T1FAD4SS2M
|2 NLM
|
| 700 |
1 |
|
|a Duan, Tianyu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Li, Hongbin
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 35(2019), 22 vom: 04. Juni, Seite 7255-7260
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
|
| 773 |
1 |
8 |
|g volume:35
|g year:2019
|g number:22
|g day:04
|g month:06
|g pages:7255-7260
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1021/acs.langmuir.9b00701
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_721
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 35
|j 2019
|e 22
|b 04
|c 06
|h 7255-7260
|