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231225s2018 xx |||||o 00| ||eng c |
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|a 10.1107/S1600577518013401
|2 doi
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|a pubmed24n0967.xml
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|a (DE-627)NLM290399807
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|a (NLM)30407195
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Wagner, Willi L
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Towards synchrotron phase-contrast lung imaging in patients - a proof-of-concept study on porcine lungs in a human-scale chest phantom
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| 264 |
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|c 2018
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 21.12.2018
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|a Date Revised 21.12.2018
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a In-line free propagation phase-contrast synchrotron tomography of the lungs has been shown to provide superior image quality compared with attenuation-based computed tomography (CT) in small-animal studies. The present study was performed to prove the applicability on a human-patient scale using a chest phantom with ventilated fresh porcine lungs. Local areas of interest were imaged with a pixel size of 100 µm, yielding a high-resolution depiction of anatomical hallmarks of healthy lungs and artificial lung nodules. Details like fine spiculations into surrounding alveolar spaces were shown on a micrometre scale. Minor differences in artificial lung nodule density were detected by phase retrieval. Since we only applied a fraction of the X-ray dose used for clinical high-resolution CT scans, it is believed that this approach may become applicable to the detailed assessment of focal lung lesions in patients in the future
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| 650 |
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4 |
|a Journal Article
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| 650 |
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|a high-resolution porcine lung imaging
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| 650 |
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|a phase retrieval
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| 650 |
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|a preclinical chest phantom
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| 650 |
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4 |
|a propagation based imaging
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| 650 |
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4 |
|a synchrotron radiation
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| 700 |
1 |
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|a Wuennemann, Felix
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Pacilé, Serena
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Albers, Jonas
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Arfelli, Fulvia
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Dreossi, Diego
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Biederer, Jürgen
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Konietzke, Philip
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Stiller, Wolfram
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wielpütz, Mark O
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Accardo, Agostino
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Confalonieri, Marco
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Cova, Maria
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lotz, Joachim
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Alves, Frauke
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kauczor, Hans Ulrich
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tromba, Giuliana
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Dullin, Christian
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Journal of synchrotron radiation
|d 1994
|g 25(2018), Pt 6 vom: 01. Nov., Seite 1827-1832
|w (DE-627)NLM09824129X
|x 1600-5775
|7 nnns
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| 773 |
1 |
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|g volume:25
|g year:2018
|g number:Pt 6
|g day:01
|g month:11
|g pages:1827-1832
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| 856 |
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|u http://dx.doi.org/10.1107/S1600577518013401
|3 Volltext
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