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231225s2018 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20180814-06
|2 doi
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|a eng
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| 100 |
1 |
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|a Orellana-Rios, Jorge
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Quantitative Fundus Autofluorescence in Non-Neovascular Age-Related Macular Degeneration
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|c 2018
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 20.03.2019
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|a Date Revised 20.03.2019
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright 2018, SLACK Incorporated.
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|a BACKGROUND AND OBJECTIVE: To use quantitative fundus autofluorescence (qAF) to analyze different stages of non-neovascular age-related macular degeneration (AMD)
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|a PATIENTS AND METHODS: In this cohort study, 38 pseudophakic patients and 36 age-matched controls participated. We performed near-infrared, spectral-domain optical coherence tomography and qAF imaging on 31 pseudophakic eyes and controls of participants older than 60 years with non-neovascular AMD phenotypes using the Spectralis HRA + OCT (Heidelberg Engineering, Heidelberg, Germany)
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|a RESULTS: The patients included in this study had a mean age of 83.9 years, and 35.7% patients were men. Mean qAF was higher in control participants than in all patients with AMD (P < .001). According to non-neovascular AMD phenotype, mean qAF levels were significantly lower in eyes with subretinal drusenoid deposits than in control eyes (P < .05). The lowest mean qAF was in patients with geographic atrophy
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|a CONCLUSION: Quantitative fundus autofluorescence of non-neovascular AMD decreases from normal to early to late AMD, suggesting that loss of lipofuscin fluorophores, not increase, signifies AMD progression. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:S34-S42.]
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|a Journal Article
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|a Multicenter Study
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4 |
|a Research Support, Non-U.S. Gov't
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| 700 |
1 |
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|a Yokoyama, Sho
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Agee, Julia M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Challa, Nayanika
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Freund, K Bailey
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yannuzzi, Lawrence A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Smith, R Theodore
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 49(2018), 10 vom: 15. Okt., Seite S34-S42
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnas
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| 773 |
1 |
8 |
|g volume:49
|g year:2018
|g number:10
|g day:15
|g month:10
|g pages:S34-S42
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|u http://dx.doi.org/10.3928/23258160-20180814-06
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