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231225s2019 xx |||||o 00| ||eng c |
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|a 10.1111/nph.15439
|2 doi
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|a pubmed24n0962.xml
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|a (DE-627)NLM288883764
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|a (NLM)30252137
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Tedeschi, Francesca
|e verfasserin
|4 aut
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|a EFFECTOR OF TRANSCRIPTION factors are novel plant-specific regulators associated with genomic DNA methylation in Arabidopsis
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|c 2019
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 21.01.2020
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2018 The Authors. New Phytologist © 2018 New Phytologist Trust.
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|a Plant-specific EFFECTORS OF TRANSCRIPTION (ET) are characterised by a variable number of highly conserved ET repeats, which are involved in zinc and DNA binding. In addition, ETs share a GIY-YIG domain, involved in DNA nicking activity. It was hypothesised that ETs might act as epigenetic regulators. Here, methylome, transcriptome and phenotypic analyses were performed to investigate the role of ET factors and their involvement in DNA methylation in Arabidopsis thaliana. Comparative DNA methylation and transcriptome analyses in flowers and seedlings of et mutants revealed ET-specific differentially expressed genes and mostly independently characteristic, ET-specific differentially methylated regions. Loss of ET function results in pleiotropic developmental defects. The accumulation of cyclobutane pyrimidine dimers after ultraviolet stress in et mutants suggests an ET function in DNA repair
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Arabidopsis thaliana
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|a DNA methylation
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|a DNA repair
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|a EFFECTOR OF TRANSCRIPTION (ET)
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|a methylome
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|a Arabidopsis Proteins
|2 NLM
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|a ET1 protein, Arabidopsis
|2 NLM
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|a ET2 protein, Arabidopsis
|2 NLM
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|a Pyrimidine Dimers
|2 NLM
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|a Transcription Factors
|2 NLM
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|a Rizzo, Paride
|e verfasserin
|4 aut
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|a Huong, Bui Thi Mai
|e verfasserin
|4 aut
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|a Czihal, Andreas
|e verfasserin
|4 aut
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|a Rutten, Twan
|e verfasserin
|4 aut
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|a Altschmied, Lothar
|e verfasserin
|4 aut
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|a Scharfenberg, Sarah
|e verfasserin
|4 aut
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|a Grosse, Ivo
|e verfasserin
|4 aut
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|a Becker, Claude
|e verfasserin
|4 aut
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|a Weigel, Detlef
|e verfasserin
|4 aut
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|a Bäumlein, Helmut
|e verfasserin
|4 aut
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|a Kuhlmann, Markus
|e verfasserin
|4 aut
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|i Enthalten in
|t The New phytologist
|d 1979
|g 221(2019), 1 vom: 01. Jan., Seite 261-278
|w (DE-627)NLM09818248X
|x 1469-8137
|7 nnns
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|g volume:221
|g year:2019
|g number:1
|g day:01
|g month:01
|g pages:261-278
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|u http://dx.doi.org/10.1111/nph.15439
|3 Volltext
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|a AR
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|d 221
|j 2019
|e 1
|b 01
|c 01
|h 261-278
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