EFFECTOR OF TRANSCRIPTION factors are novel plant-specific regulators associated with genomic DNA methylation in Arabidopsis

Bibliographische Detailangaben
Veröffentlicht in:	The New phytologist. - 1979. - 221(2019), 1 vom: 01. Jan., Seite 261-278
1. Verfasser:	Tedeschi, Francesca (VerfasserIn)
Weitere Verfasser:	Rizzo, Paride, Huong, Bui Thi Mai, Czihal, Andreas, Rutten, Twan, Altschmied, Lothar, Scharfenberg, Sarah, Grosse, Ivo, Becker, Claude, Weigel, Detlef, Bäumlein, Helmut, Kuhlmann, Markus
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2019
Zugriff auf das übergeordnete Werk:	The New phytologist
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Arabidopsis thaliana DNA methylation DNA repair EFFECTOR OF TRANSCRIPTION (ET) methylome Arabidopsis Proteins ET1 protein, Arabidopsis ET2 protein, Arabidopsis mehr... Pyrimidine Dimers Transcription Factors

Beschreibung
Zusammenfassung:	© 2018 The Authors. New Phytologist © 2018 New Phytologist Trust. Plant-specific EFFECTORS OF TRANSCRIPTION (ET) are characterised by a variable number of highly conserved ET repeats, which are involved in zinc and DNA binding. In addition, ETs share a GIY-YIG domain, involved in DNA nicking activity. It was hypothesised that ETs might act as epigenetic regulators. Here, methylome, transcriptome and phenotypic analyses were performed to investigate the role of ET factors and their involvement in DNA methylation in Arabidopsis thaliana. Comparative DNA methylation and transcriptome analyses in flowers and seedlings of et mutants revealed ET-specific differentially expressed genes and mostly independently characteristic, ET-specific differentially methylated regions. Loss of ET function results in pleiotropic developmental defects. The accumulation of cyclobutane pyrimidine dimers after ultraviolet stress in et mutants suggests an ET function in DNA repair
Beschreibung:	Date Completed 21.01.2020 Date Revised 30.09.2020 published: Print-Electronic Citation Status MEDLINE
ISSN:	1469-8137
DOI:	10.1111/nph.15439