Biophysical Mechanisms of Membrane-Thickness-Dependent MscL Gating : An All-Atom Molecular Dynamics Study

The bacterial mechanosensitive channel, MscL, is activated by membrane tension, acting as a safety valve to prevent cell lysis against hypotonic challenge. It has been established that its activation threshold decreases with membrane thickness, while the underlying mechanism remains to be solved. We...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 23 vom: 11. Juni, Seite 7432-7442
1. Verfasser:	Katsuta, Hiroki (VerfasserIn)
Weitere Verfasser:	Sawada, Yasuyuki, Sokabe, Masahiro
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2019
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Escherichia coli Proteins Ion Channels MscL protein, E coli