Nanoparticle Induced Conformational Switch Between α-Helix and β-Sheet Attenuates Immunogenic Response of MPT63

Although significant efforts have been devoted to develop nanoparticle-based biopharmaceuticals, it is not understood how protein conformation and nanoparticle surface modulate each other in optimizing the activity and/or toxicity of the biological molecules. This is particularly important for a pro...

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Publié dans:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 34(2018), 30 vom: 31. Juli, Seite 8807-8817
Auteur principal:	Sannigrahi, Achinta (Auteur)
Autres auteurs:	Chall, Sayantani, Jawed, Junaid Jibran, Kundu, Amrita, Majumdar, Subrata, Chattopadhyay, Krishnananda
Format:	Article en ligne
Langue:	English
Publié:	2018
Accès à la collection:	Langmuir : the ACS journal of surfaces and colloids
Sujets:	Journal Article Research Support, Non-U.S. Gov't Antitubercular Agents Bacterial Proteins MPT63 antigen, Mycobacterium tuberculosis