Nanoparticle Induced Conformational Switch Between α-Helix and β-Sheet Attenuates Immunogenic Response of MPT63
Although significant efforts have been devoted to develop nanoparticle-based biopharmaceuticals, it is not understood how protein conformation and nanoparticle surface modulate each other in optimizing the activity and/or toxicity of the biological molecules. This is particularly important for a pro...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 34(2018), 30 vom: 31. Juli, Seite 8807-8817
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| 1. Verfasser: |
Sannigrahi, Achinta
(VerfasserIn) |
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| Weitere Verfasser: |
Chall, Sayantani,
Jawed, Junaid Jibran,
Kundu, Amrita,
Majumdar, Subrata,
Chattopadhyay, Krishnananda |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2018
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Antitubercular Agents
Bacterial Proteins
MPT63 antigen, Mycobacterium tuberculosis |
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