Binding of HSA to Macromolecular pHPMA Based Nanoparticles for Drug Delivery : An Investigation Using Fluorescence Methods

Amphiphilic poly( N-(2-hydroxypropyl)methacrylamide) copolymers ( pHPMA) bearing cholesterol side groups in phosphate buffer saline self-assemble into nanoparticles (NPs) which can be used as tumor-targeted drug carriers. It was previously shown by us that human serum albumin (HSA) interacts weakly...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 34(2018), 27 vom: 10. Juli, Seite 7998-8006
1. Verfasser: Zhang, Xiaohan (VerfasserIn)
Weitere Verfasser: Chytil, Petr, Etrych, Tomáš, Liu, Weiwei, Rodrigues, Leticia, Winter, Gerhard, Filippov, Sergey K, Papadakis, Christine M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Drug Carriers Macromolecular Substances Serum Albumin Serum Albumin, Human ZIF514RVZR