pH-Responsive Polyion Complex Vesicle with Polyphosphobetaine Shells

When a bioactive molecule is taken into cells by endocytosis, it is sometimes unable to escape from the lysosomes, resulting in inefficient drug release. We prepared pH-responsive polyion complex (PIC) vesicles that collapse under acidic conditions such as those inside a lysosome. Furthermore, under...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 5 vom: 05. Feb., Seite 1249-1256
1. Verfasser: Ohara, Yuki (VerfasserIn)
Weitere Verfasser: Nakai, Keita, Ahmed, Sana, Matsumura, Kazuaki, Ishihara, Kazuhiko, Yusa, Shin-Ichi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't