Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints
Adaptive designs for multi-armed clinical trials have become increasingly popular recently because of their potential to shorten development times and to increase patient response. However, developing response-adaptive designs that offer patient-benefit while ensuring the resulting trial provides a...
| Veröffentlicht in: | Journal of applied statistics. - 1991. - 45(2018), 6 vom: 12., Seite 1052-1076 |
|---|---|
| 1. Verfasser: | |
| Weitere Verfasser: | |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2018
|
| Zugriff auf das übergeordnete Werk: | Journal of applied statistics |
| Schlagworte: | Journal Article Gittins index Multi-armed bandit normally distributed endpoint patient allocation response adaptive procedures sequential sampling |
| Online verfügbar |
Volltext |