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231225s2018 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.7b03403
|2 doi
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|a pubmed24n0938.xml
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|a (DE-627)NLM281438382
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|a (NLM)29485886
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
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|a Hillmann, Roland
|e verfasserin
|4 aut
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|a Characterization of Robust and Free-Standing 2D-Nanomembranes of UV-Polymerized Diacetylene Lipids
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|c 2018
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 24.09.2018
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|a Date Revised 24.09.2018
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Free-standing lipid membranes are promising as artificial functional membrane systems for application in separation, filtration, and nanopore sensing. To improve the mechanical properties of lipid membranes, UV-polymerized lipids have been introduced. We investigated free-standing as well as substrate-supported monolayers of 1-palmitoyl-2-(10,12-tricosadiynoyl)- sn-glycero-3-phosphoethanolamine (PTPE) and 1,2-bis(10,12-tricosadiynoyl)- sn-glycero-3-phosphocholine (DiynePC) and characterized them with respect to their structure, morphology, and stability. Using helium ion microscopy (HIM), we were able to visualize the integrity of the lipid 2D-nanomembranes spanning micrometer-sized voids under high-vacuum conditions. Atomic force microscopy (AFM) investigations under ambient conditions revealed formation of intact and robust pore-spanning 2D-nanomembranes up to 8 × 2 μm2 in size. Analysis by attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) verified a distinct reduction of signal at 2143 cm-1 from diacetylene groups in the 2D-nanomembranes after UV-polymerization. Further high-resolution AFM investigations of unpolymerized lipid monolayers revealed a well-ordered two-dimensional network, when deposited on highly oriented pyrolytic graphite (HOPG). These structures were inhibited for polymerized adlayers. Structural models for the molecular arrangement of the adlayers are proposed and discussed
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Lipid Bilayers
|2 NLM
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|a Lipids
|2 NLM
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|a Viefhues, Martina
|e verfasserin
|4 aut
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|a Goett-Zink, Lukas
|e verfasserin
|4 aut
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|a Gilzer, Dominic
|e verfasserin
|4 aut
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|a Hellweg, Thomas
|e verfasserin
|4 aut
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|a Gölzhäuser, Armin
|e verfasserin
|4 aut
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|a Kottke, Tilman
|e verfasserin
|4 aut
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|a Anselmetti, Dario
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 34(2018), 10 vom: 13. März, Seite 3256-3263
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:34
|g year:2018
|g number:10
|g day:13
|g month:03
|g pages:3256-3263
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|u http://dx.doi.org/10.1021/acs.langmuir.7b03403
|3 Volltext
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