YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance

YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance

© 2018 Universidad Politécnica de Madrid (UPM) New Phytologist © 2018 New Phytologist Trust.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1984. - 218(2018), 2 vom: 15. Apr., Seite 661-680
1. Verfasser: Sopeña-Torres, Sara (VerfasserIn)
Weitere Verfasser: Jordá, Lucía, Sánchez-Rodríguez, Clara, Miedes, Eva, Escudero, Viviana, Swami, Sanjay, López, Gemma, Piślewska-Bednarek, Mariola, Lassowskat, Ines, Lee, Justin, Gu, Yangnan, Haigis, Sabine, Alexander, Danny, Pattathil, Sivakumar, Muñoz-Barrios, Antonio, Bednarek, Pawel, Somerville, Shauna, Schulze-Lefert, Paul, Hahn, Michael G, Scheel, Dierk, Molina, Antonio
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. ERECTA cell wall mitogen-activated protein kinases (MAPKs) pattern recognition receptor (PRR) plant immunity receptor-like kinase (RLK) stomata mehr... Arabidopsis Proteins Pathogen-Associated Molecular Pattern Molecules Flagellin 12777-81-0 MAP Kinase Kinase Kinases EC 2.7.11.25 YODA protein, Arabidopsis
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100 1 |a Sopeña-Torres, Sara  |e verfasserin  |4 aut 
245 1 0 |a YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance 
264 1 |c 2018 
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500 |a Citation Status MEDLINE 
520 |a © 2018 Universidad Politécnica de Madrid (UPM) New Phytologist © 2018 New Phytologist Trust. 
520 |a Mitogen-activated protein kinases (MAPKs) cascades play essential roles in plants by transducing developmental cues and environmental signals into cellular responses. Among the latter are microbe-associated molecular patterns perceived by pattern recognition receptors (PRRs), which trigger immunity. We found that YODA (YDA) - a MAPK kinase kinase regulating several Arabidopsis developmental processes, like stomatal patterning - also modulates immune responses. Resistance to pathogens is compromised in yda alleles, whereas plants expressing the constitutively active YDA (CA-YDA) protein show broad-spectrum resistance to fungi, bacteria, and oomycetes with different colonization modes. YDA functions in the same pathway as ERECTA (ER) Receptor-Like Kinase, regulating both immunity and stomatal patterning. ER-YDA-mediated immune responses act in parallel to canonical disease resistance pathways regulated by phytohormones and PRRs. CA-YDA plants exhibit altered cell-wall integrity and constitutively express defense-associated genes, including some encoding putative small secreted peptides and PRRs whose impairment resulted in enhanced susceptibility phenotypes. CA-YDA plants show strong reprogramming of their phosphoproteome, which contains protein targets distinct from described MAPKs substrates. Our results suggest that, in addition to stomata development, the ER-YDA pathway regulates an immune surveillance system conferring broad-spectrum disease resistance that is distinct from the canonical pathways mediated by described PRRs and defense hormones 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
650 4 |a ERECTA 
650 4 |a cell wall 
650 4 |a mitogen-activated protein kinases (MAPKs) 
650 4 |a pattern recognition receptor (PRR) 
650 4 |a plant immunity 
650 4 |a receptor-like kinase (RLK) 
650 4 |a stomata 
650 7 |a Arabidopsis Proteins  |2 NLM 
650 7 |a Pathogen-Associated Molecular Pattern Molecules  |2 NLM 
650 7 |a Flagellin  |2 NLM 
650 7 |a 12777-81-0  |2 NLM 
650 7 |a MAP Kinase Kinase Kinases  |2 NLM 
650 7 |a EC 2.7.11.25  |2 NLM 
650 7 |a YODA protein, Arabidopsis  |2 NLM 
650 7 |a EC 2.7.11.25  |2 NLM 
700 1 |a Jordá, Lucía  |e verfasserin  |4 aut 
700 1 |a Sánchez-Rodríguez, Clara  |e verfasserin  |4 aut 
700 1 |a Miedes, Eva  |e verfasserin  |4 aut 
700 1 |a Escudero, Viviana  |e verfasserin  |4 aut 
700 1 |a Swami, Sanjay  |e verfasserin  |4 aut 
700 1 |a López, Gemma  |e verfasserin  |4 aut 
700 1 |a Piślewska-Bednarek, Mariola  |e verfasserin  |4 aut 
700 1 |a Lassowskat, Ines  |e verfasserin  |4 aut 
700 1 |a Lee, Justin  |e verfasserin  |4 aut 
700 1 |a Gu, Yangnan  |e verfasserin  |4 aut 
700 1 |a Haigis, Sabine  |e verfasserin  |4 aut 
700 1 |a Alexander, Danny  |e verfasserin  |4 aut 
700 1 |a Pattathil, Sivakumar  |e verfasserin  |4 aut 
700 1 |a Muñoz-Barrios, Antonio  |e verfasserin  |4 aut 
700 1 |a Bednarek, Pawel  |e verfasserin  |4 aut 
700 1 |a Somerville, Shauna  |e verfasserin  |4 aut 
700 1 |a Schulze-Lefert, Paul  |e verfasserin  |4 aut 
700 1 |a Hahn, Michael G  |e verfasserin  |4 aut 
700 1 |a Scheel, Dierk  |e verfasserin  |4 aut 
700 1 |a Molina, Antonio  |e verfasserin  |4 aut 
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773 1 8 |g volume:218  |g year:2018  |g number:2  |g day:15  |g month:04  |g pages:661-680 
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