YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance

YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance

© 2018 Universidad Politécnica de Madrid (UPM) New Phytologist © 2018 New Phytologist Trust.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1984. - 218(2018), 2 vom: 15. Apr., Seite 661-680
1. Verfasser: Sopeña-Torres, Sara (VerfasserIn)
Weitere Verfasser: Jordá, Lucía, Sánchez-Rodríguez, Clara, Miedes, Eva, Escudero, Viviana, Swami, Sanjay, López, Gemma, Piślewska-Bednarek, Mariola, Lassowskat, Ines, Lee, Justin, Gu, Yangnan, Haigis, Sabine, Alexander, Danny, Pattathil, Sivakumar, Muñoz-Barrios, Antonio, Bednarek, Pawel, Somerville, Shauna, Schulze-Lefert, Paul, Hahn, Michael G, Scheel, Dierk, Molina, Antonio
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. ERECTA cell wall mitogen-activated protein kinases (MAPKs) pattern recognition receptor (PRR) plant immunity receptor-like kinase (RLK) stomata mehr... Arabidopsis Proteins Pathogen-Associated Molecular Pattern Molecules Flagellin 12777-81-0 MAP Kinase Kinase Kinases EC 2.7.11.25 YODA protein, Arabidopsis
Beschreibung
Zusammenfassung:© 2018 Universidad Politécnica de Madrid (UPM) New Phytologist © 2018 New Phytologist Trust.
Mitogen-activated protein kinases (MAPKs) cascades play essential roles in plants by transducing developmental cues and environmental signals into cellular responses. Among the latter are microbe-associated molecular patterns perceived by pattern recognition receptors (PRRs), which trigger immunity. We found that YODA (YDA) - a MAPK kinase kinase regulating several Arabidopsis developmental processes, like stomatal patterning - also modulates immune responses. Resistance to pathogens is compromised in yda alleles, whereas plants expressing the constitutively active YDA (CA-YDA) protein show broad-spectrum resistance to fungi, bacteria, and oomycetes with different colonization modes. YDA functions in the same pathway as ERECTA (ER) Receptor-Like Kinase, regulating both immunity and stomatal patterning. ER-YDA-mediated immune responses act in parallel to canonical disease resistance pathways regulated by phytohormones and PRRs. CA-YDA plants exhibit altered cell-wall integrity and constitutively express defense-associated genes, including some encoding putative small secreted peptides and PRRs whose impairment resulted in enhanced susceptibility phenotypes. CA-YDA plants show strong reprogramming of their phosphoproteome, which contains protein targets distinct from described MAPKs substrates. Our results suggest that, in addition to stomata development, the ER-YDA pathway regulates an immune surveillance system conferring broad-spectrum disease resistance that is distinct from the canonical pathways mediated by described PRRs and defense hormones
Beschreibung:Date Completed 19.09.2019
Date Revised 18.03.2022
published: Print-Electronic
GENBANK: GSE79026, GSE95609, PXD006988
Citation Status MEDLINE
ISSN:1469-8137
DOI:10.1111/nph.15007