Vital ex vivo tissue labeling and pathology-guided micropunching to characterize cellular heterogeneity in the tissue microenvironment
Cellular heterogeneity within the tissue microenvironment may underlie chemotherapeutic resistance and response, enabling tumor evolution; however, this heterogeneity it is difficult to characterize. Here, we present a new approach-pathology-guided micropunching (PGM)-that enables identification and...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | BioTechniques. - 1991. - 64(2018), 1 vom: 01. Jan., Seite 13-19
|
1. Verfasser: |
Johnson, Brian P
(VerfasserIn) |
Weitere Verfasser: |
Vitek, Ross A,
Geiger, Peter G,
Huang, Wei,
Jarrard, David F,
Lang, Joshua M,
Beebe, David J |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2018
|
Zugriff auf das übergeordnete Werk: | BioTechniques
|
Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Palkovits micropunch
metabolic imaging
pathology-guided micropunching
prostate
tissue microenvironment
tumor heterogeneity
vital staining
mehr...
Reactive Oxygen Species
RNA
63231-63-0 |