Inhibition of β-Amyloid Aggregation through a Designed β-Hairpin Peptide
Designing peptide-based drugs to target the β-sheet-rich toxic intermediates during the aggregation of amyloid-β 1-42 (Aβ1-42) has been a major challenge. In general, β-sheet breaker peptides (BSBPs) are designed to complement the enthalpic interactions with the aggregating protein, and entropic eff...
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Détails bibliographiques
| Publié dans: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 34(2018), 4 vom: 30. Jan., Seite 1591-1600
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| Auteur principal: |
Jha, Anjali
(Auteur) |
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| Autres auteurs: |
Kumar, Mothukuri Ganesh,
Gopi, Hosahudya N,
Paknikar, Kishore M |
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| Format: | Article en ligne
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| Langue: | English |
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| Publié: |
2018
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| Accès à la collection: | Langmuir : the ACS journal of surfaces and colloids
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| Sujets: | Journal Article
Research Support, Non-U.S. Gov't
Amyloid beta-Peptides
Peptide Fragments
Peptides
Peptides, Cyclic |
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