Inhibition of β-Amyloid Aggregation through a Designed β-Hairpin Peptide
Designing peptide-based drugs to target the β-sheet-rich toxic intermediates during the aggregation of amyloid-β 1-42 (Aβ1-42) has been a major challenge. In general, β-sheet breaker peptides (BSBPs) are designed to complement the enthalpic interactions with the aggregating protein, and entropic eff...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 34(2018), 4 vom: 30. Jan., Seite 1591-1600
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| 1. Verfasser: |
Jha, Anjali
(VerfasserIn) |
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| Weitere Verfasser: |
Kumar, Mothukuri Ganesh,
Gopi, Hosahudya N,
Paknikar, Kishore M |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2018
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Amyloid beta-Peptides
Peptide Fragments
Peptides
Peptides, Cyclic |
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