Conserved Activity of Reassociated Homotetrameric Protein Subunits Released from Mesoporous Silica Nanoparticles

Mesoporous silica nanoparticles (MSN) with enlarged pores were prepared and characterized, and reversibly dissociated subunits of concanavalin A were entrapped in the mesopores, as shown by multiple biochemical and material characterizations. When loaded in the MSN, we demonstrated protein stability...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 34(2018), 1 vom: 09. Jan., Seite 228-233
1. Verfasser: Deodhar, Gauri V (VerfasserIn)
Weitere Verfasser: Adams, Marisa L, Joardar, Sutapa, Joglekar, Madhura, Davidson, Malcolm, Smith, William C, Mettler, Madelyn, Toler, Sydney A, Davies, Fiona K, Williams, S Kim R, Trewyn, Brian G
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Drug Carriers Protein Subunits Concanavalin A 11028-71-0 Silicon Dioxide 7631-86-9 Peptide Hydrolases EC 3.4.-