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231225s2018 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.7b02562
|2 doi
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|a pubmed24n0928.xml
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|a (NLM)29198119
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|a DE-627
|b ger
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|e rakwb
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|a eng
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|a Kim, Taeshik
|e verfasserin
|4 aut
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|a Synthesis of Fluorescent Au Nanocrystals-Silica Hybrid Nanocomposite (FLASH) with Enhanced Optical Features for Bioimaging and Photodynamic Activity
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|c 2018
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 11.09.2018
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|a Date Revised 11.09.2018
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Fluorescent Au nanocrystals (AuNCs)-silica hybrid nanocomposite (FLASH) was synthesized by co-condensation of surface-modified AuNCs. Present FLASH nanocomposite exhibited four times the enhanced photoluminescence and photocatalytic activity compared to single nanocrystals. On the basis of these enhanced optical features, we successfully demonstrated in vitro fluorescence bioimaging of introduced FLASH to human cervical cancer cell line (HeLa). Beyond the confirmation of photocatalytic activity from the photodegradation of methylene blue as a model compound, the regional selective photodynamic therapy of HeLa cells under UV irradiation was also presented. Taken together the enhanced optical features and further potential in theranostic applications, we expect that the present FLASH can be a promising tool for nanobiotechnology field
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Silanes
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|a Jang, Hongje
|e verfasserin
|4 aut
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|a Kim, Seongchan
|e verfasserin
|4 aut
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|a Lee, Jong-Hwan
|e verfasserin
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|a Kim, Sung-Yon
|e verfasserin
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|a Jeon, Noo Li
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|a Song, Joon Myong
|e verfasserin
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|a Min, Dal-Hee
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 34(2018), 1 vom: 09. Jan., Seite 173-178
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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|g volume:34
|g year:2018
|g number:1
|g day:09
|g month:01
|g pages:173-178
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|u http://dx.doi.org/10.1021/acs.langmuir.7b02562
|3 Volltext
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