|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM277376394 |
| 003 |
DE-627 |
| 005 |
20250222123403.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2017 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1093/jxb/erx373
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0924.xml
|
| 035 |
|
|
|a (DE-627)NLM277376394
|
| 035 |
|
|
|a (NLM)29069454
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Wang, Chen
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a ghr-miR5272a-mediated regulation of GhMKK6 gene transcription contributes to the immune response in cotton
|
| 264 |
|
1 |
|c 2017
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 07.01.2019
|
| 500 |
|
|
|a Date Revised 07.01.2019
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a CommentIn: J Exp Bot. 2017 Dec 16;68(21-22):5685-5687. doi: 10.1093/jxb/erx385. - PMID 29267907
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology.
|
| 520 |
|
|
|a Fusarium wilt is a major biotic stress affecting the productivity of cotton (Gossypium hirsutum). Although mitogen-activated protein kinase (MAPK) cascades play critical roles in plant disease resistance, their intricate regulation under fungal stress remains unclear, especially with regards to microRNA-mediated regulation of MAPK gene expression. In this study, we report that the MAPK kinase gene GhMKK6 and ghr-miR5272a work together in cotton resistance to Fusarium wilt. Silencing GhMKK6 in cotton decreased resistance to F. oxysporum by repressing the expression of known disease-resistance genes. Furthermore, although GhMKK6 played a positive role in disease resistance, excessive GhMKK6 activation caused an excessive hypersensitive response. ghr-miR5272a, a major regulator, prevents this excessive response by regulating GhMKK6 expression. ghr-miR5272a targets the GhMKK6 3'-untranslated region in cotton. Overexpressing miR5272a decreased the expression of GhMKK6 and disease-resistance genes, and increased sensitivity to F. oxysporum, yielding a similar phenotype to GhMKK6-silenced cotton. Overall, these results demonstrate that the ghr-miR5272a-mediated regulation of GhMKK6 expression contributes to the immune response in cotton, and reveal a new feedback loop mechanism in plant disease response
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
4 |
|a Cotton
|
| 650 |
|
4 |
|a Fusarium oxysporum
|
| 650 |
|
4 |
|a GhMKK6
|
| 650 |
|
4 |
|a Gossypium hirsutum
|
| 650 |
|
4 |
|a feedback loop
|
| 650 |
|
4 |
|a ghr-miR5272a
|
| 650 |
|
4 |
|a miRNA
|
| 650 |
|
7 |
|a MicroRNAs
|2 NLM
|
| 650 |
|
7 |
|a Plant Proteins
|2 NLM
|
| 650 |
|
7 |
|a RNA, Plant
|2 NLM
|
| 650 |
|
7 |
|a Mitogen-Activated Protein Kinase Kinases
|2 NLM
|
| 650 |
|
7 |
|a EC 2.7.12.2
|2 NLM
|
| 700 |
1 |
|
|a He, Xiaowen
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Xinxin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhang, Shuxin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Guo, Xingqi
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 68(2017), 21-22 vom: 16. Dez., Seite 5895-5906
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
|
| 773 |
1 |
8 |
|g volume:68
|g year:2017
|g number:21-22
|g day:16
|g month:12
|g pages:5895-5906
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1093/jxb/erx373
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 68
|j 2017
|e 21-22
|b 16
|c 12
|h 5895-5906
|