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231225s2017 xx |||||o 00| ||eng c |
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|a 10.1107/S1600577517009572
|2 doi
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|a pubmed25n0917.xml
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|a (DE-627)NLM275348636
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|a (NLM)28862621
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a Esteve, Emmanuel
|e verfasserin
|4 aut
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1 |
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|a Flyscan opportunities in medicine
|b the case of quantum rattle based on gold quantum dots
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Revised 20.11.2019
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a The new rapid scan method, Flyscan mode, implemented on the DiffAbs beamline at Synchrotron SOLEIL, allows fast micro-X-ray fluorescence data acquisition. It paves the way for applications in the biomedical field where a large amount of data is needed to generate meaningful information for the clinician. This study presents a complete set of data acquired after injection of gold-cluster-enriched mesoporous silica nanospheres, used as potential theranostic vectors, into rats. While classical X-ray fluorescence investigations (using step-by-step acquisitions) are based on a limited number of samples (approximately one per day at the DiffAbs beamline), the Flyscan mode has enabled gathering information on the interaction of nanometer-scale vectors in different organs such as liver, spleen and kidney at the micrometer scale, for five rats, in only a single five-day synchrotron shift. Moreover, numerous X-ray absorption near-edge structure spectra, which are beam-time-consuming taking into account the low concentration of these theranostic vectors, were collected
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|a Journal Article
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|a Flyscan method
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|a X-ray fluorescence
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|a XANES
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|a gold-cluster-enriched mesoporous silica nanospheres
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|a theranostic vectors
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|a Reguer, Solenn
|e verfasserin
|4 aut
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|a Boissiere, Cédric
|e verfasserin
|4 aut
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|a Chanéac, Corinne
|e verfasserin
|4 aut
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|a Lugo, Gustavo
|e verfasserin
|4 aut
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|a Jouanneau, Chantal
|e verfasserin
|4 aut
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|a Mocuta, Cristian
|e verfasserin
|4 aut
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|a Thiaudière, Dominique
|e verfasserin
|4 aut
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| 700 |
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|a Leclercq, Nicolas
|e verfasserin
|4 aut
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| 700 |
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|a Leyh, Bernard
|e verfasserin
|4 aut
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| 700 |
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|a Greisch, Jean François
|e verfasserin
|4 aut
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| 700 |
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|a Berthault, Julien
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Daudon, Michel
|e verfasserin
|4 aut
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| 700 |
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|a Ronco, Pierre
|e verfasserin
|4 aut
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| 700 |
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|a Bazin, Dominique
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Journal of synchrotron radiation
|d 1994
|g 24(2017), Pt 5 vom: 01. Sept., Seite 991-999
|w (DE-627)NLM09824129X
|x 1600-5775
|7 nnns
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| 773 |
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|g volume:24
|g year:2017
|g number:Pt 5
|g day:01
|g month:09
|g pages:991-999
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|u http://dx.doi.org/10.1107/S1600577517009572
|3 Volltext
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|h 991-999
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