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231225s2017 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.7b01333
|2 doi
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|a pubmed24n0911.xml
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|a (DE-627)NLM273363689
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|a (NLM)28658955
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Wu, Bozhen
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Salt-Induced Regenerative Surface for Bacteria Killing and Release
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 23.01.2019
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|a Date Revised 23.01.2019
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Antibacterial surfaces with both bacteria killing and release functions show great promise in biological and biomedical applications, in particular for reusable medical devices. However, these surfaces either require a sophisticated technique to create delicate structures or need rigorous stimuli to trigger the functions, greatly limiting their practical application. In this study, we made a step forward by developing a simple system based on a salt-responsive polyzwitterionic brush. Specifically, the salt-responsive brush of poly(3-(dimethyl (4-vinylbenzyl) ammonium) propyl sulfonate) (polyDVBAPS) was endowed with bactericidal function by grafting an effective bactericide, i.e., triclosan (TCS). This simple functionalization successfully integrated the bacteria attach/release function of polyDVBAPS and bactericidal function of TCS. As a result, the surface could kill more than 95% attached bacteria and, subsequently, could rapidly detach ∼97% bacteria after gently shaking in 1.0 M NaCl for 10 min. More importantly, such high killing efficiency and release rate could be well retained (unchanged effectiveness of both killing and release after four severe killing/release cycles), indicating the highly efficient regeneration and long-term reusability of this system. This study not only contributes zwitterionic polymers by conferring new functions but also provides a new, highly efficient and reliable surface for "killing-release" antibacterial strategy
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Anti-Bacterial Agents
|2 NLM
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| 650 |
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7 |
|a Polymers
|2 NLM
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| 650 |
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|a Sodium Chloride
|2 NLM
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| 650 |
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|a 451W47IQ8X
|2 NLM
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| 650 |
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|a Triclosan
|2 NLM
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| 650 |
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7 |
|a 4NM5039Y5X
|2 NLM
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| 700 |
1 |
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|a Zhang, Lixun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Huang, Lei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Xiao, Shengwei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yang, Yin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhong, Mingqiang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yang, Jintao
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 33(2017), 28 vom: 18. Juli, Seite 7160-7168
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
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|g volume:33
|g year:2017
|g number:28
|g day:18
|g month:07
|g pages:7160-7168
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|u http://dx.doi.org/10.1021/acs.langmuir.7b01333
|3 Volltext
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