Autoantibodies, detection methods and panels for diagnosis of Sjögren's syndrome

Copyright © 2017 Elsevier Inc. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 182(2017) vom: 01. Sept., Seite 24-29
1. Verfasser: Shen, Long (VerfasserIn)
Weitere Verfasser: Suresh, Lakshmanan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Review Research Support, Non-U.S. Gov't Autoantibodies Detection methods Sjögren's syndrome Antibodies, Antinuclear BPIFA2 protein, human Carrier Proteins Immunoglobulins mehr... Microfilament Proteins Peptides, Cyclic SP1 antigen SS-A antibodies SS-B antibodies Salivary Proteins and Peptides cyclic citrullinated peptide fodrin Rheumatoid Factor 9009-79-4 Carbonic Anhydrases EC 4.2.1.1 carbonic anhydrase VI
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520 |a The presence of autoantibodies is one of several hallmarks of Sjögren's Syndrome, the detection of serum autoantibodies has a central role in the diagnosis and classification of Sjögren's syndrome. In this review, we will discuss autoantibodies that are helpful in the diagnosis of Sjögren's syndrome. This includes the traditional autoantibodies for disease classification (ANA, Anti-Ro/SSA, Anti-La/SSB, RF), autoantibodies identified from mouse models (Anti-SP1, Anti- PSP, Anti-CA6, and anti-alpha fodrin) and autoantibodies associated with other autoimmune disease (ACA, AMA, and Anti-CCP). We will also review the methods for the detection of autoantibodies and associated challenges for clinical results reporting. The significance of using an autoantibody panel for the diagnosis of SS will be also be reviewed 
650 4 |a Journal Article 
650 4 |a Review 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Autoantibodies 
650 4 |a Detection methods 
650 4 |a Sjögren's syndrome 
650 7 |a Antibodies, Antinuclear  |2 NLM 
650 7 |a Autoantibodies  |2 NLM 
650 7 |a BPIFA2 protein, human  |2 NLM 
650 7 |a Carrier Proteins  |2 NLM 
650 7 |a Immunoglobulins  |2 NLM 
650 7 |a Microfilament Proteins  |2 NLM 
650 7 |a Peptides, Cyclic  |2 NLM 
650 7 |a SP1 antigen  |2 NLM 
650 7 |a SS-A antibodies  |2 NLM 
650 7 |a SS-B antibodies  |2 NLM 
650 7 |a Salivary Proteins and Peptides  |2 NLM 
650 7 |a cyclic citrullinated peptide  |2 NLM 
650 7 |a fodrin  |2 NLM 
650 7 |a Rheumatoid Factor  |2 NLM 
650 7 |a 9009-79-4  |2 NLM 
650 7 |a Carbonic Anhydrases  |2 NLM 
650 7 |a EC 4.2.1.1  |2 NLM 
650 7 |a carbonic anhydrase VI  |2 NLM 
650 7 |a EC 4.2.1.1  |2 NLM 
700 1 |a Suresh, Lakshmanan  |e verfasserin  |4 aut 
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