Autoantibodies, detection methods and panels for diagnosis of Sjögren's syndrome

Bibliographische Detailangaben
Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 182(2017) vom: 01. Sept., Seite 24-29
1. Verfasser:	Shen, Long (VerfasserIn)
Weitere Verfasser:	Suresh, Lakshmanan
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2017
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Review Research Support, Non-U.S. Gov't Autoantibodies Detection methods Sjögren's syndrome Antibodies, Antinuclear BPIFA2 protein, human Carrier Proteins Immunoglobulins mehr... Microfilament Proteins Peptides, Cyclic SP1 antigen SS-A antibodies SS-B antibodies Salivary Proteins and Peptides cyclic citrullinated peptide fodrin Rheumatoid Factor 9009-79-4 Carbonic Anhydrases EC 4.2.1.1 carbonic anhydrase VI

Beschreibung
Zusammenfassung:	Copyright © 2017 Elsevier Inc. All rights reserved. The presence of autoantibodies is one of several hallmarks of Sjögren's Syndrome, the detection of serum autoantibodies has a central role in the diagnosis and classification of Sjögren's syndrome. In this review, we will discuss autoantibodies that are helpful in the diagnosis of Sjögren's syndrome. This includes the traditional autoantibodies for disease classification (ANA, Anti-Ro/SSA, Anti-La/SSB, RF), autoantibodies identified from mouse models (Anti-SP1, Anti- PSP, Anti-CA6, and anti-alpha fodrin) and autoantibodies associated with other autoimmune disease (ACA, AMA, and Anti-CCP). We will also review the methods for the detection of autoantibodies and associated challenges for clinical results reporting. The significance of using an autoantibody panel for the diagnosis of SS will be also be reviewed
Beschreibung:	Date Completed 06.11.2017 Date Revised 31.03.2022 published: Print-Electronic Citation Status MEDLINE
ISSN:	1521-7035
DOI:	10.1016/j.clim.2017.03.017