Analysis of three risk stratification systems in a Saudi population

INTRODUCTION: Coronary artery disease is the leading cause of death worldwide. Although there are a number of algorithms in use for determining the risk of coronary artery disease and thus predicting future cardiovascular events, the data available regarding their validity among the Saudi population...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Journal of the Saudi Heart Association. - 1999. - 29(2017), 2 vom: 21. Apr., Seite 96-101
1. Verfasser: Abazid, Rami (VerfasserIn)
Weitere Verfasser: Al Saqqa, Hanna, Smettei, Osama
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Journal of the Saudi Heart Association
Schlagworte:Journal Article ACC/AHA Pooled Cohort Risk Equation Framingham Risk Score Multi-Ethnic Study of Atherosclerosis score
LEADER 01000caa a22002652c 4500
001 NLM270618627
003 DE-627
005 20250221111805.0
007 cr uuu---uuuuu
008 231224s2017 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.jsha.2016.06.002  |2 doi 
028 5 2 |a pubmed25n0901.xml 
035 |a (DE-627)NLM270618627 
035 |a (NLM)28373783 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Abazid, Rami  |e verfasserin  |4 aut 
245 1 0 |a Analysis of three risk stratification systems in a Saudi population 
264 1 |c 2017 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Revised 30.09.2020 
500 |a published: Print-Electronic 
500 |a Citation Status PubMed-not-MEDLINE 
520 |a INTRODUCTION: Coronary artery disease is the leading cause of death worldwide. Although there are a number of algorithms in use for determining the risk of coronary artery disease and thus predicting future cardiovascular events, the data available regarding their validity among the Saudi population are insufficient 
520 |a OBJECTIVE: We studied the validity of three clinical score systems in predicting a high risk population defined as having excessive coronary calcification: the American College of Cardiology/American Heart Association (ACC/AHA) Pooled Cohort Risk Equation, the Framingham Risk Score, and the European Systematic Coronary Risk Evaluation 
520 |a METHODS: We analyzed data from 462 patients aged ⩾40 years. High-risk features were if the Coronary Calcium Score was either >400 or in the ⩾75th percentile using Multi-Ethnic Study of Atherosclerosis (MESA) score. The scores for the three algorithms were then calculated using the participants' clinical data 
520 |a RESULTS: A total of 87 (18.8%) patients were positive for coronary calcification. Among them, 60 (13%) were classified as being at high risk according to the MESA score. Analyzing these patients by the ACC/AHA Pooled Cohort Risk Equation resulted in nine (15%) as being at low risk, 12 (20%) at intermediate risk, and 39 (65%) at high risk. The Framingham Risk classification resulted in 14 (23%) being at low risk, 13 (22%) at intermediate risk, and 33 (55%) at high risk. The European Systematic Coronary Risk Evaluation risk classification showed 24 (40%) at low risk, 12 (20%) at intermediate risk, and 24 (40%) at high risk, with p < 0.0001 
520 |a CONCLUSION: The ACC/AHA Pooled Cohort Risk Equation has superior risk ​ calibration compared to the other two risk-score algorithms in a Saudi population 
650 4 |a Journal Article 
650 4 |a ACC/AHA Pooled Cohort Risk Equation 
650 4 |a Framingham Risk Score 
650 4 |a Multi-Ethnic Study of Atherosclerosis score 
700 1 |a Al Saqqa, Hanna  |e verfasserin  |4 aut 
700 1 |a Smettei, Osama  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Journal of the Saudi Heart Association  |d 1999  |g 29(2017), 2 vom: 21. Apr., Seite 96-101  |w (DE-627)NLM098225227  |x 1016-7315  |7 nnas 
773 1 8 |g volume:29  |g year:2017  |g number:2  |g day:21  |g month:04  |g pages:96-101 
856 4 0 |u http://dx.doi.org/10.1016/j.jsha.2016.06.002  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 29  |j 2017  |e 2  |b 21  |c 04  |h 96-101