Proteomic Analysis of HDAC3 Selective Inhibitor in the Regulation of Inflammatory Response of Primary Microglia
HDAC3 has been shown to regulate inflammation. However, the role of HDAC3 in primary microglia is largely unknown. RGFP966 is a newly discovered selective HDAC3 inhibitor. In this study, we used protein mass spectrometry to analyze protein alterations in LPS-treated primary microglia with the applic...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Neural plasticity. - 1998. - 2017(2017) vom: 28., Seite 6237351
|
1. Verfasser: |
Xia, Mingxu
(VerfasserIn) |
Weitere Verfasser: |
Zhao, Qiuchen,
Zhang, He,
Chen, Yanting,
Yuan, Zengqiang,
Xu, Yun,
Zhang, Meijuan |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2017
|
Zugriff auf das übergeordnete Werk: | Neural plasticity
|
Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Acrylamides
Histone Deacetylase Inhibitors
Lipopolysaccharides
Phenylenediamines
RGFP966
STAT3 Transcription Factor
STAT5 Transcription Factor
Stat3 protein, mouse
mehr...
Toll-Like Receptor 2
Histone Deacetylases
EC 3.5.1.98
histone deacetylase 3 |