Proteomic Analysis of HDAC3 Selective Inhibitor in the Regulation of Inflammatory Response of Primary Microglia

HDAC3 has been shown to regulate inflammation. However, the role of HDAC3 in primary microglia is largely unknown. RGFP966 is a newly discovered selective HDAC3 inhibitor. In this study, we used protein mass spectrometry to analyze protein alterations in LPS-treated primary microglia with the applic...

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Veröffentlicht in:Neural plasticity. - 1998. - 2017(2017) vom: 28., Seite 6237351
1. Verfasser: Xia, Mingxu (VerfasserIn)
Weitere Verfasser: Zhao, Qiuchen, Zhang, He, Chen, Yanting, Yuan, Zengqiang, Xu, Yun, Zhang, Meijuan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Acrylamides Histone Deacetylase Inhibitors Lipopolysaccharides Phenylenediamines RGFP966 STAT3 Transcription Factor STAT5 Transcription Factor Stat3 protein, mouse mehr... Toll-Like Receptor 2 Histone Deacetylases EC 3.5.1.98 histone deacetylase 3