A Zwitterionic-Shielded Carrier with pH-Modulated Reversible Self-Assembly for Gene Transfection
Cationic vectors are ideal candidates for gene delivery thanks to their capability to carry large gene inserts and their scalable production. However, their cationic density gives rise to high cytotoxicity. We present the proper designed core-shell polyplexes made of either poly(ethylene imine) (PEI...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 33(2017), 8 vom: 28. Feb., Seite 1914-1926
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| 1. Verfasser: |
Shih, Yuju
(VerfasserIn) |
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| Weitere Verfasser: |
Venault, Antoine,
Tayo, Lemmuel L,
Chen, Sheng-Han,
Higuchi, Akon,
Deratani, Andre,
Chinnathambi, Arunachalam,
Alharbi, Sulaiman Ali,
Quemener, Damien,
Chang, Yung |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2017
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Imines
Methacrylates
Nylons
Polyethylenes
Polymers
poly(2-(dimethylamino)ethyl methacrylate)
poly(ethylene imine)
DNA
9007-49-2 |
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