A Zwitterionic-Shielded Carrier with pH-Modulated Reversible Self-Assembly for Gene Transfection

Cationic vectors are ideal candidates for gene delivery thanks to their capability to carry large gene inserts and their scalable production. However, their cationic density gives rise to high cytotoxicity. We present the proper designed core-shell polyplexes made of either poly(ethylene imine) (PEI...

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Publié dans:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 33(2017), 8 vom: 28. Feb., Seite 1914-1926
Auteur principal:	Shih, Yuju (Auteur)
Autres auteurs:	Venault, Antoine, Tayo, Lemmuel L, Chen, Sheng-Han, Higuchi, Akon, Deratani, Andre, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Quemener, Damien, Chang, Yung
Format:	Article en ligne
Langue:	English
Publié:	2017
Accès à la collection:	Langmuir : the ACS journal of surfaces and colloids
Sujets:	Journal Article Research Support, Non-U.S. Gov't Imines Methacrylates Nylons Polyethylenes Polymers poly(2-(dimethylamino)ethyl methacrylate) poly(ethylene imine) DNA 9007-49-2