Restoring Spinal Noradrenergic Inhibitory Tone Attenuates Pain Hypersensitivity in a Rat Model of Parkinson's Disease

In the present study, we investigated whether restoring descending noradrenergic inhibitory tone can attenuate pain in a PD rat model, which was established by stereotaxic infusion of 6-hydroxydopamine (6-OHDA) into the bilateral striatum (CPu). PD rats developed thermal and mechanical hypersensitiv...

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Veröffentlicht in:Neural plasticity. - 1998. - 2016(2016) vom: 01., Seite 6383240
1. Verfasser: Cao, Lei-Fang (VerfasserIn)
Weitere Verfasser: Peng, Xiao-Yan, Huang, Ya, Wang, Bing, Zhou, Feng-Ming, Cheng, Ruo-Xiao, Chen, Li-Hua, Luo, Wei-Feng, Liu, Tong
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Benzylamines Levodopa 46627O600J Oxidopamine 8HW4YBZ748 DSP 4 PQ1P7JP5C1 Norepinephrine X4W3ENH1CV