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231224s2016 xx |||||o 00| ||eng c |
| 024 |
7 |
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|a 10.1111/nph.14105
|2 doi
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|a pubmed24n0875.xml
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|a (DE-627)NLM262629348
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|a (NLM)27439310
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Gibbs, Daniel J
|e verfasserin
|4 aut
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| 245 |
1 |
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|a From start to finish
|b amino-terminal protein modifications as degradation signals in plants
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 26.01.2018
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.
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|a Contents 1188 I. 1188 II. 1189 III. 1190 IV. 1191 V. 1192 1192 References 1192 SUMMARY: The amino- (N-) terminus (Nt) of a protein can undergo a diverse array of co- and posttranslational modifications. Many of these create degradation signals (N-degrons) that mediate protein destruction via the N-end rule pathway of ubiquitin-mediated proteolysis. In plants, the N-end rule pathway has emerged as a major system for regulated control of protein stability. Nt-arginylation-dependent degradation regulates multiple growth, development and stress responses, and recently identified functions of Nt-acetylation can also be linked to effects on the in vivo half-lives of Nt-acetylated proteins. There is also increasing evidence that N-termini could act as important protein stability determinants in plastids. Here we review recent advances in our understanding of the relationship between the nature of protein N-termini, Nt-processing events and proteolysis in plants
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|a Journal Article
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|a Review
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|a Research Support, Non-U.S. Gov't
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|a N-degron
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|a N-end rule
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|a N-terminus
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|a Nt-acetylation
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| 650 |
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|a protease
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| 650 |
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|a protein modification
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| 650 |
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|a proteolysis
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| 650 |
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|a ubiquitin proteasome system
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| 650 |
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|a Plant Proteins
|2 NLM
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| 700 |
1 |
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|a Bailey, Mark
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tedds, Hannah M
|e verfasserin
|4 aut
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| 700 |
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|a Holdsworth, Michael J
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t The New phytologist
|d 1979
|g 211(2016), 4 vom: 20. Sept., Seite 1188-94
|w (DE-627)NLM09818248X
|x 1469-8137
|7 nnns
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| 773 |
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|g volume:211
|g year:2016
|g number:4
|g day:20
|g month:09
|g pages:1188-94
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|u http://dx.doi.org/10.1111/nph.14105
|3 Volltext
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