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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201601754
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|a pubmed24n0873.xml
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|a eng
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|a Richardson, Joseph J
|e verfasserin
|4 aut
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|a Polymer Capsules for Plaque-Targeted In Vivo Delivery
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|c 2016
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|a Text
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 11.09.2018
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a ErratumIn: Adv Mater. 2016 Sep;28(36):7820. - PMID 27717055
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|a Citation Status MEDLINE
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|a © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Targeted polymer capsules can selectively bind to unstable plaques in mice after intravenous injection. Different formulations of the capsules are explored with a synthetic/biopolymer hybrid capsule showing the best stability and small-molecule drug retention. The synthetic polymer is composed of pH-sensitive blocks (PDPA), low-binding blocks (PEG), and click-groups for postfunctionalization with targeting peptides specific to plaques
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|a Journal Article
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|a click-chemistry
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|a degradation
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|a nanomedicine
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|a polymer blends
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|a templating
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|a Capsules
|2 NLM
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|a Polymers
|2 NLM
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|a Choy, Mei Y
|e verfasserin
|4 aut
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|a Guo, Junling
|e verfasserin
|4 aut
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|a Liang, Kang
|e verfasserin
|4 aut
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|a Alt, Karen
|e verfasserin
|4 aut
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|a Ping, Yuan
|e verfasserin
|4 aut
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|a Cui, Jiwei
|e verfasserin
|4 aut
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|a Law, Lok S
|e verfasserin
|4 aut
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|a Hagemeyer, Christoph E
|e verfasserin
|4 aut
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|a Caruso, Frank
|e verfasserin
|4 aut
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 28(2016), 35 vom: 30. Sept., Seite 7703-7
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|g volume:28
|g year:2016
|g number:35
|g day:30
|g month:09
|g pages:7703-7
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|u http://dx.doi.org/10.1002/adma.201601754
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