Lipidation Effect on Surface Adsorption and Associated Fibrillation of the Model Protein Insulin
Lipidation of proteins is used in the pharmaceutical field to increase the therapeutic efficacy of proteins. In this study, we investigate the effect of a 14-carbon fatty acid modification on the adsorption behavior of human insulin to a hydrophobic solid surface and the subsequent fibrillation deve...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 32(2016), 28 vom: 19. Juli, Seite 7241-9
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| 1. Verfasser: |
Hedegaard, Sofie Fogh
(VerfasserIn) |
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| Weitere Verfasser: |
Cárdenas, Marité,
Barker, Robert,
Jorgensen, Lene,
van de Weert, Marco |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2016
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Insulin
Protein Aggregates |
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