Lipidation Effect on Surface Adsorption and Associated Fibrillation of the Model Protein Insulin
Lipidation of proteins is used in the pharmaceutical field to increase the therapeutic efficacy of proteins. In this study, we investigate the effect of a 14-carbon fatty acid modification on the adsorption behavior of human insulin to a hydrophobic solid surface and the subsequent fibrillation deve...
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Détails bibliographiques
| Publié dans: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 32(2016), 28 vom: 19. Juli, Seite 7241-9
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| Auteur principal: |
Hedegaard, Sofie Fogh
(Auteur) |
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| Autres auteurs: |
Cárdenas, Marité,
Barker, Robert,
Jorgensen, Lene,
van de Weert, Marco |
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| Format: | Article en ligne
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| Langue: | English |
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| Publié: |
2016
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| Accès à la collection: | Langmuir : the ACS journal of surfaces and colloids
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| Sujets: | Journal Article
Research Support, Non-U.S. Gov't
Insulin
Protein Aggregates |
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