OsHSD1, a hydroxysteroid dehydrogenase, is involved in cuticle formation and lipid homeostasis in rice

Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Plant science : an international journal of experimental plant biology. - 1985. - 249(2016) vom: 01. Aug., Seite 35-45
1. Verfasser: Zhang, Zhe (VerfasserIn)
Weitere Verfasser: Cheng, Zhi-Jun, Gan, Lu, Zhang, Huan, Wu, Fu-Qing, Lin, Qi-Bing, Wang, Jiu-Lin, Wang, Jie, Guo, Xiu-Ping, Zhang, Xin, Zhao, Zhi-Chao, Lei, Cai-Lin, Zhu, Shan-Shan, Wang, Chun-Ming, Wan, Jian-Min
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Plant science : an international journal of experimental plant biology
Schlagworte:Journal Article Cuticular wax Hydroxysteroid dehydrogenase Lipid Oil body Oryza sativa Plant Proteins Hydroxysteroid Dehydrogenases EC 1.1.-
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520 |a Cuticular wax, a hydrophobic layer on the surface of all aerial plant organs, has essential roles in plant growth and survival under various environments. Here we report a wax-deficient rice mutant oshsd1 with reduced epicuticular wax crystals and thicker cuticle membrane. Quantification of the wax components and fatty acids showed elevated levels of very-long-chain fatty acids (VLCFAs) and accumulation of soluble fatty acids in the leaves of the oshsd1 mutant. We determined the causative gene OsHSD1, a member of the short-chain dehydrogenase reductase family, through map-based cloning. It was ubiquitously expressed and responded to cold stress and exogenous treatments with NaCl or brassinosteroid analogs. Transient expression of OsHSD1-tagged green fluorescent protein revealed that OsHSD1 localized to both oil bodies and endoplasmic reticulum (ER). Dehydrogenase activity assays demonstrated that OsHSD1 was an NAD(+)/NADP(+)-dependent sterol dehydrogenase. Furthermore, OsHSD1 mutation resulted in faster protein degradation, but had no effect on the dehydrogenase activity. Together, our data indicated that OsHSD1 plays a specialized role in cuticle formation and lipid homeostasis, probably by mediating sterol signaling. This work provides new insights into oil-body associated proteins involved in wax and lipid metabolism 
650 4 |a Journal Article 
650 4 |a Cuticular wax 
650 4 |a Hydroxysteroid dehydrogenase 
650 4 |a Lipid 
650 4 |a Oil body 
650 4 |a Oryza sativa 
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650 7 |a Hydroxysteroid Dehydrogenases  |2 NLM 
650 7 |a EC 1.1.-  |2 NLM 
700 1 |a Cheng, Zhi-Jun  |e verfasserin  |4 aut 
700 1 |a Gan, Lu  |e verfasserin  |4 aut 
700 1 |a Zhang, Huan  |e verfasserin  |4 aut 
700 1 |a Wu, Fu-Qing  |e verfasserin  |4 aut 
700 1 |a Lin, Qi-Bing  |e verfasserin  |4 aut 
700 1 |a Wang, Jiu-Lin  |e verfasserin  |4 aut 
700 1 |a Wang, Jie  |e verfasserin  |4 aut 
700 1 |a Guo, Xiu-Ping  |e verfasserin  |4 aut 
700 1 |a Zhang, Xin  |e verfasserin  |4 aut 
700 1 |a Zhao, Zhi-Chao  |e verfasserin  |4 aut 
700 1 |a Lei, Cai-Lin  |e verfasserin  |4 aut 
700 1 |a Zhu, Shan-Shan  |e verfasserin  |4 aut 
700 1 |a Wang, Chun-Ming  |e verfasserin  |4 aut 
700 1 |a Wan, Jian-Min  |e verfasserin  |4 aut 
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856 4 0 |u http://dx.doi.org/10.1016/j.plantsci.2016.05.005  |3 Volltext 
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