Seizure-Induced Regulations of Amyloid-β, STEP61, and STEP61 Substrates Involved in Hippocampal Synaptic Plasticity
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline. Pathologic accumulation of soluble amyloid-β (Aβ) oligomers impairs synaptic plasticity and causes epileptic seizures, both of which contribute to cognitive dysfunction in AD. However, wheth...
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Bibliographische Detailangaben
| Veröffentlicht in: | Neural plasticity. - 1998. - 2016(2016) vom: 14., Seite 2123748
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| 1. Verfasser: |
Jang, Sung-Soo
(VerfasserIn) |
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| Weitere Verfasser: |
Royston, Sara E,
Lee, Gunhee,
Wang, Shuwei,
Chung, Hee Jung |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2016
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Amyloid beta-Peptides
NR2B NMDA receptor
Receptors, N-Methyl-D-Aspartate
Protein Tyrosine Phosphatases
EC 3.1.3.48 |
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