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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1107/S1600577515024856
|2 doi
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|a pubmed25n0859.xml
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|a (DE-627)NLM257861998
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|a (NLM)26917136
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Wieland, D C F
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Studying solutions at high shear rates
|b a dedicated microfluidics setup
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|c 2016
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 13.12.2016
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|a Date Revised 30.12.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The development of a dedicated small-angle X-ray scattering setup for the investigation of complex fluids at different controlled shear conditions is reported. The setup utilizes a microfluidics chip with a narrowing channel. As a consequence, a shear gradient is generated within the channel and the effect of shear rate on structure and interactions is mapped spatially. In a first experiment small-angle X-ray scattering is utilized to investigate highly concentrated protein solutions up to a shear rate of 300000 s(-1). These data demonstrate that equilibrium clusters of lysozyme are destabilized at high shear rates
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a aggregation
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|a beamline setup
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|a complex solutions
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|a lysozyme
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|a microfluidics
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| 650 |
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|a protein interaction
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| 650 |
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|a rheology
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|a shear
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| 650 |
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|a small-angle X-ray scattering (SAXS)
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| 700 |
1 |
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|a Garamus, V M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zander, T
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Krywka, C
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Dedinaite, A
|e verfasserin
|4 aut
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1 |
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|a Claesson, P M
|e verfasserin
|4 aut
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|a Willumeit-Römer, R
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Journal of synchrotron radiation
|d 1994
|g 23(2016), 2 vom: 01. März, Seite 480-6
|w (DE-627)NLM09824129X
|x 1600-5775
|7 nnns
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| 773 |
1 |
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|g volume:23
|g year:2016
|g number:2
|g day:01
|g month:03
|g pages:480-6
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|u http://dx.doi.org/10.1107/S1600577515024856
|3 Volltext
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